Publications

Vet Pathol 2026

Artificial intelligence–based detection of small and intermediate-to-large lymphocytes for cytologic diagnosis of canine lymphoma

Wei-Chien Kao, Yui H. Kam, Cheng Zhang, Kate Marciano, Jera’lyne Hyland, Candice P. Chu

Veterinary Pathology, 2026 · online ahead of print

Trained YOLOv11 to identify individual lymphocytes in smartphone photomicrographs of canine lymph node aspirates, using 25,761 annotated cells across 680 images from 34 intermediate-to-large B-cell lymphoma and 11 non-lymphoma aspirates. Merging intermediate and large lymphocytes into a single label improved cell-level classification, reaching 87.60% average precision, 84.71% average recall, mAP50 of 89.33% and an F1 score of 86.02% on the independent test set, with correct diagnoses inferred for every test aspirate.

Vet Clin North Am Small Anim Pract 2026

Computer vision and deep learning in small animal cytology and slide review

Candice P. Chu

Veterinary Clinics of North America: Small Animal Practice, 2026

An invited review of computer vision fundamentals for veterinary cytology, current scientific progress, and publication guidelines. Examines how nine veterinary organizations address AI in their position or policy statements, alongside industrial implementation and the case for AI literacy in continuing education.

Veterinary Pathology 2026

Applying artificial intelligence to automate clinical data extraction from veterinary electronic health records: a practical guidance and comparative scoping review

Yumi Chang, Candice P. Chu

Veterinary Pathology, 2026 · special issue on artificial intelligence

Screened 5,796 papers and included 54 studies (23 veterinary, 31 human) on AI-based clinical data extraction. Provides a step-by-step framework for data preparation, platform and privacy decisions, and prompt engineering, with a worked case study extracting 62 variables from canine pancreatitis records.

Front Vet Sci 2026

Curriculum framework for artificial intelligence literacy in veterinary education

Yu-Ting (Avery) Huang, Candice P. Chu

Frontiers in Veterinary Science, 2026

A five-module framework for teaching AI literacy in veterinary curricula, with an implementation case study of VTPB 948 at Texas A&M University.

Animals 2025

Renal single-Cell RNA sequencing and digital cytometry in dogs with X-linked hereditary nephropathy

Candice P. Chu, Daniel Osorio, and Mary B. Nabity

Animals, 2025

Applied single-cell RNA sequencing to profile renal cortical tissues from dogs with X-linked hereditary nephropathy. Recovered over 13,000 cells and identified 11 cell types. Digital cytometry confirmed disease-related shifts in renal cell composition across CKD progression.

Vet Clin Pathol 2025

Urinary microRNA as biomarkers for chronic kidney disease in dogs and cats: updates and challenges

Candice P. Chu, and Mary B. Nabity

Veterinary Clinical Pathology, 2025

Comprehensive review of urinary miRNAs as non-invasive biomarkers for CKD in companion animals. Addresses preanalytical factors, RNA isolation methods, sequencing analysis, and normalization strategies.

Front Vet Sci 2024

ChatGPT in veterinary medicine: a practical guidance of generative artificial intelligence in clinics, education, and research

C. P. Chu

Frontiers in Veterinary Science, 2024

Practical synthesis of ChatGPT applications in veterinary clinical, educational, and research domains. Actionable guidance for professionals without a programming background.

J Vet Intern Med 2024

MicroRNA-126 in dogs with immune complex-mediated glomerulonephritis

A. D. Cherry, C. P. Chu, R. E. Cianciolo, and 3 more authors

Journal of Veterinary Internal Medicine, 2024

Vet Clin Pathol 2024

What is your diagnosis? Large perianal mass in a dog

C. P. Chu, M. B. Nabity, B. F. Porter, and 1 more author

Veterinary Clinical Pathology, 2024

Cell 2023

Serotonin reduction in post-acute sequelae of viral infection

A. C. Wong, A. S. Devason, I. C. Umana, and 56 more authors

Cell, 2023

Sci Rep 2021

Small RNA sequencing evaluation of renal microRNA biomarkers in dogs with X-linked hereditary nephropathy

C. P. Chu, S. Liu, W. Song, and 2 more authors

Scientific Reports, 2021

Vet Clin Pathol 2019

Comparison of RNA isolation and library preparation methods for small RNA sequencing of canine biofluids

C. P. Chu, and M. B. Nabity

Veterinary Clinical Pathology, 2019

PLOS ONE 2018

Expression profiling of disease progression in canine model of Duchenne muscular dystrophy

C. Brinkmeyer-Langford, C. Chu, C. Balog-Alvarez, and 4 more authors

PLOS ONE, 2018

Sci Rep 2017

RNA-seq of serial kidney biopsies obtained during progression of chronic kidney disease from dogs with X-linked hereditary nephropathy

C. P. Chu, J. A. Hokamp, R. E. Cianciolo, and 4 more authors

Scientific Reports, 2017

Nature Career column, 2024

Banish the PDF-hunting blues with these AI and digital tools

C. P. Chu

Nature, 2024

Veterinary Focus, 2024

Round cell tumour cytology in dogs

Candice P. Chu

Veterinary Focus, April 2024

The Vetiverse, 2024

7 key aspects of pathology informatics in veterinary medicine

Candice P. Chu

The Vetiverse, February 2024

Clinician's Brief, 2023

Top 3 conditions missed by skipping a urinalysis

Candice P. Chu

Clinician's Brief, September 2023

Book chapter, 2024

Differential diagnosis chapters: antithrombin III, fibrinogen, amylase, lipase, lipids, fibrin degradation products, pancytopenia

Candice P. Chu

Plumb's Pro, October 2024